Procyclidine Intravenous for Adults

Who can administer

May be administered by registered competent doctor or nurse/midwife

Important information

• Unlicensed preparation

Available preparations

Kemadrin 10mg per 2mL ampoule

Reconstitution

Already in solution

Draw up using a 5 micron filter needle

Infusion fluids

Not required - product ready for administration

Methods of intravenous administration

Slow intravenous injection

• Administer required dose over 3 to 5 minutes ^{(ref 1)}

Dose in adults

Acute dystonia

• A dose of 5 to 10mg is usually effective within five to ten minutes
• Occasionally, patients may need more than 10mg, and may require up to 30 minutes to obtain relief
• Advised daily maximum dose by intravenous injection = 20mg
• Elderly patients may require a reduction in dose

Other indications

• Similar doses are used intravenously as those given orally
• Usually given intravenously only when unable to take oral medications
• Elderly patients may require a reduction in dose

Storage

Store below 25⁰C

References

SPC (UK) 16/05/2018

1: Medusa Injectable medicines Guide- downloaded 16/03/2022

2: BNF- accessed online via Medicines complete 20/10/21

Therapeutic classification

Anticholinergic