Additrace N (trace elements) Intravenous Infusion for Adults

Who can administer

May be administered by registered competent doctor or nurse/midwife

Available preparations

Additrace N 10ml ampoule

Reconstitution

Already in solution

Dilute further prior to administration

Infusion fluids

Sodium chloride 0.9% or Glucose 5% ^{(ref 1)}

Methods of intravenous administration

Intermittent intravenous infusion ^{(ref 1)}

• Add one vial (10ml) to 100ml infusion fluid and administer over a minimum of two to three hours
• If also on Solivito N and Vitlipid N, the Additrace may be added to the same infusion bag ^{(ref 2)}.
  • Must use Sodium Chloride 0.9% as the infusion fluid in this situation
  • Must protect from light if this combination used
  • Invert the infusion bag several times to ensure adequate mixing

Dose in adults

Usual dose

• One vial administered by infusion over at least two to three hours (this long infusion time is to minimise renal losses)^{(ref 1)}

Monitoring

• If treatment is continued for more than four weeks, blood manganese levels should be checked

Further information

Each 10ml vial contains the following:

Iron (as ferric chloride)	20 micromol
Zinc (as zinc chloride)	77 micromol
Manganese (as manganese chloride)	1 micromol
Copper (as copper chloride)	6 micromol
Chromium (as chromic chloride)	0.2 micromol
Selenium (as sodium selenite)	1 micromol
Molybdenum (sodium molybdate)	0.2 micromol
Fluorine (as sodium fluoride)	50 micromol
Iodine (as potassium iodide)	1 micromol

Storage

Store below 25⁰C

References

SPC October 2021

1:  Information on file from Fresenius Kabi 'Administration of micronutrients separately from parenteral nutrition' 12th July 2022

2: Data on file from Fresenius Kabi November 2020

Therapeutic classification

Intravenous nutrition