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Mesna Intravenous for Adults
Who can administer
May be administered by registered competent doctor or nurse/midwife
Important information
- This is not a cytotoxic agent - cytotoxic handling precautions do not apply
- A minimum urine output of 100ml/hr should be maintained during therapy
Available preparations
Uromitexan 400mg in 4ml ampoule
Uromitexan 1000mg in 10ml ampoule
Reconstitution
Already in solution
Draw up using a 5 micron filter needle
Infusion fluids
Sodium chloride 0.9% or Glucose 5%
Methods of intravenous administration
Intermittent intravenous infusion (ref 1)
- Administer as per chemotherapy/renal protocols
- Usually given over 15 to 30 minutes
Continuous intravenous infusion
- Administer as per chemotherapy protocols
Dose in adults
As per chemotherapy/renal protocols
Storage
Store below 250C
References
SPC December 2018
1: Injectable Medicines Guide. Medusa downloaded 2nd May 2019
Therapeutic classification
Agent to prevent against urothelial toxicity associated with cyclophosphamide or ifosfamide