Administration RESTRICTED - see Appendix 1
Phenylephrine hydrochloride Injection 100micrograms/mL solution for injection/infusion (2mg/20mL)
Phenylephrine hydrochloride pre-filled syringe 50microgram/mL (500micrograms in 10mL)
Already in solution
Not required- already in solution
See under 'Dose' for which route of administration to use
Continuous intravenous infusion (administer using an electronically controlled infusion device)
Slow intravenous injection(ref 1)
Hypotension - by continuous intravenous infusion - ICU, CCU, or other critical care areas only | ||
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Initial dose |
Initially 25 to 50micrograms/minute (0.25 to 0.5mL/minute using a 100microgram/mL solution) |
|
Subsequently |
25 to 100microgram/minute (0.25 to 1mL/minute using a 100microgram/mL solution), adjusted according to response. This corresponds to 15 to 60ml/hour |
|
Note: there are references to higher doses in the literature e.g.BNF |
Hypotension - by slow intravenous injection
Store below 250C
Phenylephrine (Aguettant) SPC 27/06/2024
1: Injectable Medicines Administration Guide Medusa- downloaded March 2025
2: Martindale, accessed online via medicinescomplete March 2025
Sympathomimetic vasoconstrictor