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Mesna Intravenous for Adults
Who can administer
May be administered by registered competent doctor or nurse/midwife
Important information
- This is not a cytotoxic agent - cytotoxic handling precautions do not apply
- A minimum urine output of 100mL/hour should be maintained during therapy and the urine monitored for haematuria and proteinuria throughout the treatment period
Available preparations
Uromitexan 400mg in 4mL ampoule
Uromitexan 1000mg in 10mL ampoule
Reconstitution
Already in solution
Draw up using a 5 micron filter needle
Infusion fluids
Sodium chloride 0.9% or Glucose 5%
Methods of intravenous administration
Intermittent intravenous infusion
- Administer as per chemotherapy/renal protocols
- Usually given over 15 to 30 minutes
Continuous intravenous infusion
- Administer as per chemotherapy protocols
Dose in adults
As per chemotherapy/renal protocols
Storage
Store below 250C
References
SPC December 2018
Therapeutic classification
Agent to prevent against urothelial toxicity associated with cyclophosphamide or ifosfamide