Cyclizine Intravenous for Adults

Who can administer

May be administered by registered competent doctor or nurse/midwife

Valoid 50mg per 1ml ampoule

Already in solution

Draw up using a 5 micron filter needle

Not applicable - product ready for use

Slow intravenous injection

Administer over at least 3 minutes ^{(ref 1)}as rapid intravenous injection can lead to symptoms similar to those of overdose
If the volume is too small to be given as a slow intravenous injection, it may be diluted with 5 to 10ml Water for injections, Sodium chloride 0.9% or Glucose 5%. Immediately after dilution, and again just before administration, check the solution for signs of precipitation. Discard if there is any cloudiness or haze formation (unlicensed) ^{(ref 1)}

Usual dose

Nausea and vomiting: 50mg, repeated up to three times daily
Prevention of post-operative nausea: Give 50mg, 20 minutes before anticipated end of surgery
Prevention of regurgitation and aspiration during emergency surgery: Give 25mg before induction of general anaesthesia

Case reports of paralysis in patients using intravenous cyclizine - use with particular caution in patients with underlying neuromuscular disorders
Cyclizine can have a hypotensive effect when given by the intravenous route
Extravasation is likely to cause tissue damage due to its low pH ^{(ref 1)}
Cyclizine is extremely irritant and can cause injection site reactions, including vein tracking, erythema, pain, rash, thrombophlebitis and blisters ^{(ref 1)}

Store below 25⁰C

SPC July 2018

1: Injectable Medicines administration guide, downloaded from Medusa 14/10/2021

Drug used in nausea and vertigo

IV Guide Type